Altered DNA Methylation in the Developing Brains of Rats Genetically Prone to High versus Low Anxiety
There is growing evidence of abnormal epigenetic processes playing a role in the neurobiology of psychiatric disorders, although the precise nature of these anomalies remains largely unknown. To study neurobiological (including epigenetic) factors that influence emotionality, we use rats bred for di...
Gorde:
Egile Nagusiak: | Chelsea R. McCoy, Matthew E. Glover, Leigh T. Flynn, Rebecca K. Simmons, Joshua L. Cohen, Travis Ptacek, Elliot J. Lefkowitz, Nateka L. Jackson, Huda Akil, Xiaowei Wu, Sarah M. Clinton |
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Formatua: | Artigo |
Hizkuntza: | ingelesa |
Argitaratua: |
2019
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Sarrera elektronikoa: | https://doi.org/10.1523/jneurosci.1157-15.2019 https://www.jneurosci.org/content/jneuro/39/16/3144.full.pdf |
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Genetic predisposition to high anxiety- and depression-like behavior coincides with diminished DNA methylation in the adult rat amygdala
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DNA Methylation in the Developing Hippocampus and Amygdala of Anxiety-Prone versus Risk-Taking Rats
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