Altered DNA Methylation in the Developing Brains of Rats Genetically Prone to High versus Low Anxiety

Altered DNA Methylation in the Developing Brains of Rats Genetically Prone to High versus Low Anxiety

There is growing evidence of abnormal epigenetic processes playing a role in the neurobiology of psychiatric disorders, although the precise nature of these anomalies remains largely unknown. To study neurobiological (including epigenetic) factors that influence emotionality, we use rats bred for di...

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Bibliografiske detaljer
Main Authors:	Chelsea R. McCoy, Matthew E. Glover, Leigh T. Flynn, Rebecca K. Simmons, Joshua L. Cohen, Travis Ptacek, Elliot J. Lefkowitz, Nateka L. Jackson, Huda Akil, Xiaowei Wu, Sarah M. Clinton
Format:	Artigo
Sprog:	engelsk
Udgivet:	2019
Online adgang:	https://doi.org/10.1523/jneurosci.1157-15.2019 https://www.jneurosci.org/content/jneuro/39/16/3144.full.pdf
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Lignende værker

Altered DNA Methylation in the Developing Brains of Rats Genetically Prone to High versus Low Anxiety
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Genetic predisposition to high anxiety- and depression-like behavior coincides with diminished DNA methylation in the adult rat amygdala
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DNA methylation in the developing hippocampus and amygdala of anxiety-prone versus risk-taking rats
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DNA Methylation in the Developing Hippocampus and Amygdala of Anxiety-Prone versus Risk-Taking Rats
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A paternal methyl donor depleted diet leads to increased anxiety- and depression-like behavior in adult rat offspring
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Early-life exposure to the SSRI paroxetine exacerbates depression-like behavior in anxiety/depression-prone rats
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Oxidative metabolism alterations in the emotional brain of anxiety-prone rats
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miR-101a-3p and Ezh2 modulate anxiety-like behavior in high-responder rats
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Altered metabolic activity in the developing brain of rats predisposed to high versus low depression-like behavior
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Rats bred for high anxiety exhibit distinct fear-related coping behavior, hippocampal physiology, and synaptic plasticity-related gene expression
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Neonatal maternal separation stress elicits lasting DNA methylation changes in the hippocampus of stress-reactive Wistar Kyoto rats
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DNA methylation markers in the postnatal developing rat brain
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Neonatal maternal separation stress elicits lasting <scp>DNA</scp> methylation changes in the hippocampus of stress‐reactive Wistar Kyoto rats
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DNA methylation markers in the postnatal developing rat brain
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