Involvement of Lamin B1 Reduction in Accelerated Cellular Senescence during Chronic Obstructive Pulmonary Disease Pathogenesis

Involvement of Lamin B1 Reduction in Accelerated Cellular Senescence during Chronic Obstructive Pulmonary Disease Pathogenesis

Downregulation of lamin B1 has been recognized as a crucial step for development of full senescence. Accelerated cellular senescence linked to mechanistic target of rapamycin kinase (MTOR) signaling and accumulation of mitochondrial damage has been implicated in chronic obstructive pulmonary disease...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Nayuta Saito, Jun Araya, Saburo Ito, Kazuya Tsubouchi, Shunsuke Minagawa, Hiromichi Hara, Akihiko Ito, Takayuki Nakano, Yusuke Hosaka, Akihiro Ichikawa, Tsukasa Kadota, Masahiro Yoshida, Yu Fujita, Hirofumi Utsumi, Yusuke Kurita, Kenji Kobayashi, Mitsuo Hashimoto, Hiroshi Wakui, Takanori Numata, Yumi Kaneko, Hisatoshi Asano, Makoto Odaka, Takashi Ohtsuka, Toshiaki Morikawa, Katsutoshi Nakayama, Kazuyoshi Kuwano
Formato: Artigo
Idioma:inglés
Publicado: 2019
Acceso en liña:https://doi.org/10.4049/jimmunol.1801293
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Internet

https://doi.org/10.4049/jimmunol.1801293

Títulos similares