Differential effects of N-acetylcysteine on retinal degeneration in two mouse models of normal tension glaucoma

Abstract N -acetylcysteine (NAC) is widely used as a mucolytic agent and as an antidote to paracetamol overdose. NAC serves as a precursor of cysteine and stimulates the synthesis of glutathione in neural cells. Suppressing oxidative stress in the retina may be an effective therapeutic strategy for...

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Main Authors: Hiroki Sano, Kazuhiko Namekata, Atsuko Kimura, Hiroshi Shitara, Xiaoli Guo, Chikako Harada, Yoshinori Mitamura, Takayuki Harada
格式: Artigo
语言:英语
出版: 2019
在线阅读:https://doi.org/10.1038/s41419-019-1365-z
https://www.nature.com/articles/s41419-019-1365-z.pdf
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