TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment

TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment

The telomeric protein TRF2 is overexpressed in several human malignancies and contributes to tumorigenesis even though the molecular mechanism is not completely understood. By using a high-throughput approach based on the multiplexed Luminex X-MAP technology, we demonstrated that TRF2 dramatically a...

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Autori principali: Pasquale Zizza, Roberto Dinami, Manuela Porru, Chiara Cingolani, Erica Salvati, Angela Rizzo, Carmen D’Angelo, Eleonora Petti, Carla Azzurra Amoreo, Marcella Mottolese, Isabella Sperduti, Angela Chambery, Rosita Russo, Paola Ostano, Giovanna Chiorino, Giovanni Blandino, Andrea Sacconi, Julien Cherfils‐Vicini, Carlo Leonetti, Éric Gilson, Annamaria Biroccio
Natura: Artigo
Lingua:inglese
Pubblicazione: 2019
Accesso online:https://doi.org/10.1093/nar/gkz041
https://academic.oup.com/nar/article-pdf/47/7/3365/28467596/gkz041.pdf
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Accesso online

https://doi.org/10.1093/nar/gkz041
https://academic.oup.com/nar/article-pdf/47/7/3365/28467596/gkz041.pdf

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