YAP and TAZ Heterogeneity in Primary Liver Cancer: An Analysis of Its Prognostic and Diagnostic Role
Primary liver cancer comprises a diverse group of liver tumors. The heterogeneity of these tumors is seen as one of the obstacles to finding an effective therapy. The Hippo pathway, with its downstream transcriptional co-activator Yes-associated protein (YAP) and transcriptional co-activator with PD...
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Glavni autori: | Matthias Van Haele, Iván M. Moya, Ruçhan Karaman, Guy Rens, J. Snoeck, Olivier Govaere, Frederik Nevens, Chris Verslype, Baki Topal, Diethard Monbaliu, Georg Halder, Tania Roskams |
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Format: | Artigo |
Jezik: | engleski |
Izdano: |
2019
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Online pristup: | https://doi.org/10.3390/ijms20030638 https://www.mdpi.com/1422-0067/20/3/638/pdf?version=1549024629 |
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Slični predmeti
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YAP and TAZ Heterogeneity in Primary Liver Cancer: An Analysis of Its Prognostic and Diagnostic Role
od: Van Haele, Matthias, i dr.
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Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice
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