Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura

Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura

In acquired thrombotic thrombocytopenic purpura (TTP), an immune-mediated deficiency of the von Willebrand factor–cleaving protease ADAMTS13 allows unrestrained adhesion of von Willebrand factor multimers to platelets and microthrombosis, which result in thrombocytopenia, hemolytic anemia, and tissu...

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Main Authors: Marie Scully, Spero R. Cataland, Flora Peyvandi, Paul Coppo, Paul Knöbl, Johanna A. Kremer Hovinga, Ara Metjian, Javier de la Rubia, Katerina Pavenski, Filip Callewaert, Debjit Biswas, Hilde De Winter, Robert K. Zeldin
格式: Artigo
語言:英语
出版: 2019
在線閱讀:https://doi.org/10.1056/nejmoa1806311
https://www.nejm.org/doi/pdf/10.1056/NEJMoa1806311?articleTools=true
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https://doi.org/10.1056/nejmoa1806311
https://www.nejm.org/doi/pdf/10.1056/NEJMoa1806311?articleTools=true

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