Prostate cancer cells and exosomes in acidic condition show increased carbonic anhydrase IX expression and activity

Acidity and hypoxia are crucial phenotypes of tumour microenvironment both contributing to the selection of malignant cells under a micro evolutionistic pressure. During the tumour progression, nanovesicles, called exosomes and the metalloenzyme carbonic anhydrase IX (CA IX) affect the tumour growth...

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Hlavní autoři: Mariantonia Logozzi, Clemente Capasso, Rossella Di Raimo, Sonia Del Prete, Davide Mizzoni, Mario Falchi, Claudiu T. Supuran, Stefano Fais
Médium: Artigo
Jazyk:angličtina
Vydáno: 2019
On-line přístup:https://doi.org/10.1080/14756366.2018.1538980
https://www.tandfonline.com/doi/pdf/10.1080/14756366.2018.1538980?needAccess=true
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