Bone marrow MSCs in MDS: contribution towards dysfunctional hematopoiesis and potential targets for disease response to hypomethylating therapy

The study of myelodysplastic syndromes (MDS) in murine models has now indicated the possible involvement of the bone marrow microenvironment in the generation of dysplastic hematopoietic cells. However, there is scant work on patient samples and the role of hypomethylating agents on the bone marrow...

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Bibliographic Details
Main Authors: Zhiyong Poon, Niraja Dighe, Subhashree Venkatesan, Alice M.S. Cheung, Xiubo Fan, Sudipto Bari, Monalisa Hota, Sujoy Ghosh, William Ying Khee Hwang
Format: Artigo
Language:English
Published: 2018
Online Access:https://doi.org/10.1038/s41375-018-0310-y
https://www.nature.com/articles/s41375-018-0310-y.pdf
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