Bone marrow MSCs in MDS: contribution towards dysfunctional hematopoiesis and potential targets for disease response to hypomethylating therapy
The study of myelodysplastic syndromes (MDS) in murine models has now indicated the possible involvement of the bone marrow microenvironment in the generation of dysplastic hematopoietic cells. However, there is scant work on patient samples and the role of hypomethylating agents on the bone marrow...
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Main Authors: | , , , , , , , , |
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Format: | Artigo |
Language: | English |
Published: |
2018
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Online Access: | https://doi.org/10.1038/s41375-018-0310-y https://www.nature.com/articles/s41375-018-0310-y.pdf |
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