Bone marrow MSCs in MDS: contribution towards dysfunctional hematopoiesis and potential targets for disease response to hypomethylating therapy

The study of myelodysplastic syndromes (MDS) in murine models has now indicated the possible involvement of the bone marrow microenvironment in the generation of dysplastic hematopoietic cells. However, there is scant work on patient samples and the role of hypomethylating agents on the bone marrow...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Zhiyong Poon, Niraja Dighe, Subhashree Venkatesan, Alice M.S. Cheung, Xiubo Fan, Sudipto Bari, Monalisa Hota, Sujoy Ghosh, William Ying Khee Hwang
Format: Artigo
Sprache:Englisch
Veröffentlicht: 2018
Online-Zugang:https://doi.org/10.1038/s41375-018-0310-y
https://www.nature.com/articles/s41375-018-0310-y.pdf
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!