Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA

Benign prostatic hyperplasia and associated lower urinary tract symptoms (BPH/LUTS) are common conditions affecting the majority of elderly males. Here we report the results of a genome-wide association study of symptomatic BPH/LUTS in 20,621 patients and 280,541 controls of European ancestry, from...

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Main Authors: Jūlı́us Guðmundsson, Jon K. Sigurdsson, Lilja Stefánsdóttir, Bjarni A. Agnarsson, Helgi J. Ísaksson, Ólafur Andri Stefánsson, Sigurjón A. Guðjónsson, Daníel F. Guðbjartsson, Gísli Másson, Michael L. Frigge, Simon Stacey, Patrick Sulem, Gísli H. Halldórsson, Vinicius Tragante, Hilma Hólm, Guðmundur I. Eyjólfsson, Ólöf Sigurðardóttir, Ísleifur Ólafsson, Þorvaldur Jónsson, Eiríkur Jónsson, Rósa B. Barkardóttir, Rafn Hilmarsson, Folkert W. Asselbergs, Guðmundur Geirsson, Unnur Þorsteinsdóttir, Þórunn Rafnar, Guðmar Þorleifsson, Kāri Stefánsson
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Acesso em linha:https://doi.org/10.1038/s41467-018-06920-9
https://www.nature.com/articles/s41467-018-06920-9.pdf
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