Effect of crizanlizumab on pain crises in subgroups of patients with sickle cell disease: A SUSTAIN study analysis

Abstract The cell adhesion molecule P‐selectin plays a key role in the pathogenesis of a vaso‐occlusive crisis (VOC) in patients with sickle cell disease (SCD). In the double‐blind, placebo‐controlled phase 2 SUSTAIN study, crizanlizumab (humanized, anti‐P‐selectin monoclonal antibody) 5 mg/kg signi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Abdullah Kutlar, Julie Kanter, Darla Liles, Ofelia Álvarez, Rodolfo Delfini Cançado, João Ricardo Friedrisch, Jennifer Knight‐Madden, Andreas Bruederle, Michael Shi, Zewen Zhu, Kenneth I. Ataga
Fformat: Artigo
Iaith:Saesneg
Cyhoeddwyd: 2018
Mynediad Ar-lein:https://doi.org/10.1002/ajh.25308
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ajh.25308
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!