Loperamide, pimozide, and STF-62247 trigger autophagy-dependent cell death in glioblastoma cells

Loperamide, pimozide, and STF-62247 trigger autophagy-dependent cell death in glioblastoma cells

Abstract Autophagy is a well-described degradation mechanism that promotes cell survival upon nutrient starvation and other forms of cellular stresses. In addition, there is growing evidence showing that autophagy can exert a lethal function via autophagic cell death (ACD). As ACD has been implicate...

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Autors principals:	Svenja Zielke, Nina Meyer, Muriel Mari, Khalil Abou‐El‐Ardat, Fulvio Reggiori, Sjoerd J. L. van Wijk, Donat Kögel, Simone Fulda
Format:	Artigo
Idioma:	anglès
Publicat:	2018
Accés en línia:	https://doi.org/10.1038/s41419-018-1003-1 https://www.nature.com/articles/s41419-018-1003-1.pdf
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