High-Definition Analysis of Host Protein Stability during Human Cytomegalovirus Infection Reveals Antiviral Factors and Viral Evasion Mechanisms

High-Definition Analysis of Host Protein Stability during Human Cytomegalovirus Infection Reveals Antiviral Factors and Viral Evasion Mechanisms

Human cytomegalovirus (HCMV) is an important pathogen with multiple immune evasion strategies, including virally facilitated degradation of host antiviral restriction factors. Here, we describe a multiplexed approach to discover proteins with innate immune function on the basis of active degradation...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Katie Nightingale, Kai‐Min Lin, Benjamin J. Ravenhill, Colin Davies, Luís Nobre, Ceri A. Fielding, Eva Růčková, Alice Fletcher-Etherington, Lior Soday, Hester Nichols, Daniel Sugrue, Eddie C. Y. Wang, Pablo Moreno, Yagnesh Umrania, Edward L. Huttlin, Robin Antrobus, Andrew J. Davison, Gavin W. G. Wilkinson, Richard J. Stanton, Peter Tomašec, Michael P. Weekes
Médium: Artigo
Jazyk:angličtina
Vydáno: 2018
On-line přístup:https://doi.org/10.1016/j.chom.2018.07.011
https://www.cell.com/article/S1931312818303810/pdf
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Internet

https://doi.org/10.1016/j.chom.2018.07.011
https://www.cell.com/article/S1931312818303810/pdf

Podobné jednotky