High-Definition Analysis of Host Protein Stability during Human Cytomegalovirus Infection Reveals Antiviral Factors and Viral Evasion Mechanisms

Human cytomegalovirus (HCMV) is an important pathogen with multiple immune evasion strategies, including virally facilitated degradation of host antiviral restriction factors. Here, we describe a multiplexed approach to discover proteins with innate immune function on the basis of active degradation...

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書誌詳細
主要な著者: Katie Nightingale, Kai‐Min Lin, Benjamin J. Ravenhill, Colin Davies, Luís Nobre, Ceri A. Fielding, Eva Růčková, Alice Fletcher-Etherington, Lior Soday, Hester Nichols, Daniel Sugrue, Eddie C. Y. Wang, Pablo Moreno, Yagnesh Umrania, Edward L. Huttlin, Robin Antrobus, Andrew J. Davison, Gavin W. G. Wilkinson, Richard J. Stanton, Peter Tomašec, Michael P. Weekes
フォーマット: Artigo
言語:英語
出版事項: 2018
オンライン・アクセス:https://doi.org/10.1016/j.chom.2018.07.011
https://www.cell.com/article/S1931312818303810/pdf
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