High-Definition Analysis of Host Protein Stability during Human Cytomegalovirus Infection Reveals Antiviral Factors and Viral Evasion Mechanisms

High-Definition Analysis of Host Protein Stability during Human Cytomegalovirus Infection Reveals Antiviral Factors and Viral Evasion Mechanisms

Human cytomegalovirus (HCMV) is an important pathogen with multiple immune evasion strategies, including virally facilitated degradation of host antiviral restriction factors. Here, we describe a multiplexed approach to discover proteins with innate immune function on the basis of active degradation...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Katie Nightingale, Kai‐Min Lin, Benjamin J. Ravenhill, Colin Davies, Luís Nobre, Ceri A. Fielding, Eva Růčková, Alice Fletcher-Etherington, Lior Soday, Hester Nichols, Daniel Sugrue, Eddie C. Y. Wang, Pablo Moreno, Yagnesh Umrania, Edward L. Huttlin, Robin Antrobus, Andrew J. Davison, Gavin W. G. Wilkinson, Richard J. Stanton, Peter Tomašec, Michael P. Weekes
Formato: Artigo
Lenguaje:inglés
Publicado: 2018
Acceso en línea:https://doi.org/10.1016/j.chom.2018.07.011
https://www.cell.com/article/S1931312818303810/pdf
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Sea el primero en dejar un comentario!
Primero debe ingresar al sistema

Ejemplares similares