High-Definition Analysis of Host Protein Stability during Human Cytomegalovirus Infection Reveals Antiviral Factors and Viral Evasion Mechanisms
Human cytomegalovirus (HCMV) is an important pathogen with multiple immune evasion strategies, including virally facilitated degradation of host antiviral restriction factors. Here, we describe a multiplexed approach to discover proteins with innate immune function on the basis of active degradation...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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格式: | Artigo |
语言: | 英语 |
出版: |
2018
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在线阅读: | https://doi.org/10.1016/j.chom.2018.07.011 https://www.cell.com/article/S1931312818303810/pdf |
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