Multigene Hereditary Cancer Panels Reveal High-Risk Pancreatic Cancer Susceptibility Genes
The relevance of inherited pathogenic mutations in cancer predisposition genes in pancreatic cancer is not well understood. We aimed to assess the characteristics of patients with pancreatic cancer referred for hereditary cancer genetic testing and to estimate the risk of pancreatic cancer associate...
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| Autori principali: | , , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | inglese |
| Pubblicazione: |
2018
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| Accesso online: | https://doi.org/10.1200/po.17.00291 https://ascopubs.org/doi/pdfdirect/10.1200/PO.17.00291 |
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| Riassunto: | The relevance of inherited pathogenic mutations in cancer predisposition genes in pancreatic cancer is not well understood. We aimed to assess the characteristics of patients with pancreatic cancer referred for hereditary cancer genetic testing and to estimate the risk of pancreatic cancer associated with mutations in panel-based cancer predisposition genes in this high-risk population. |
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