Sporadic Parkinson’s disease derived neuronal cells show disease-specific mRNA and small RNA signatures with abundant deregulation of piRNAs
Differentiated neurons established via iPSCs from patients that suffer from familial Parkinson’s disease (PD) have allowed insights into the mechanisms of neurodegeneration. In the larger cohort of patients with sporadic PD, iPSC based information on disease specific cellular phenotypes is rare. We...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | angličtina |
| Vydáno: |
2018
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| On-line přístup: | https://doi.org/10.1186/s40478-018-0561-x https://actaneurocomms.biomedcentral.com/track/pdf/10.1186/s40478-018-0561-x |
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