Modulation of M1/M2 polarization by capsaicin contributes to the survival of dopaminergic neurons in the lipopolysaccharide-lesioned substantia nigra in vivo

Abstract The present study examined the neuroprotective effects of capsaicin (CAP) and explored their underlying mechanisms in a lipopolysaccharide (LPS)-lesioned inflammatory rat model of Parkinson’s dieases (PD). LPS was unilaterally injected into the substantia nigra (SN) in the absence or presen...

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Main Authors: Eugene Bok, Young Cheul Chung, Ki‐Suk Kim, Hyung Hwan Baik, Won-Ho Shin, Byung Kwan Jin
格式: Artigo
语言:英语
出版: 2018
在线阅读:https://doi.org/10.1038/s12276-018-0111-4
https://www.nature.com/articles/s12276-018-0111-4.pdf
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