Consistent signatures of selection from genomic analysis of pairs of temporal and spatial Plasmodium falciparum populations from The Gambia

Genome sequences of 247 Plasmodium falciparum isolates collected in The Gambia in 2008 and 2014 were analysed to identify changes possibly related to the scale-up of antimalarial interventions that occurred during this period. Overall, there were 15 regions across the genomes with signatures of posi...

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Hlavní autoři: Alfred Amambua‐Ngwa, David Jeffries, Roberto Amato, Archibald Worwui, Karim Mané, Sukai Ceesay, Haddy Nyang, Davis Nwakanma, Joseph Okebe, Dominic Kwiatkowski, David J. Conway, Umberto D’Alessandro
Médium: Artigo
Jazyk:angličtina
Vydáno: 2018
On-line přístup:https://doi.org/10.1038/s41598-018-28017-5
https://www.nature.com/articles/s41598-018-28017-5.pdf
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