Characterisation of immunoparesis in newly diagnosed myeloma and its impact on progression-free and overall survival in both old and recent myeloma trials

Characterisation of immunoparesis in newly diagnosed myeloma and its impact on progression-free and overall survival in both old and recent myeloma trials

We measured immunosuppression at myeloma diagnosis and assessed the impact on survival in 5826 UK myeloma trial patients. Polyclonal immunoglobulin levels were below normal in 85% of patients and above normal in only 0.4% of cases for IgA, 0.2% for IgM and no cases for IgG. Immunoparesis had a great...

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Hlavní autoři: Jennifer Heaney, John P. Campbell, Gulnaz Iqbal, David A. Cairns, Alex Richter, J. A. Child, Walter M. Gregory, Graham Jackson, Martin Kaiser, Roger G. Owen, Faith E. Davies, Gareth J. Morgan, Janet Dunn, Mark T. Drayson
Médium: Artigo
Jazyk:angličtina
Vydáno: 2018
On-line přístup:https://doi.org/10.1038/s41375-018-0163-4
https://www.nature.com/articles/s41375-018-0163-4.pdf
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https://doi.org/10.1038/s41375-018-0163-4
https://www.nature.com/articles/s41375-018-0163-4.pdf

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