Characterization and validation of potential therapeutic targets based on the molecular signature of patient-derived xenografts in gastric cancer
Patient-derived xenograft (PDX) models with definite molecular signature are attractive preclinical models for development of novel targeted drugs. Here, we profiled and explored potential therapeutic targets based on characterized PDX models for advanced gastric cancer (AGC). The genomic variation...
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Hlavní autoři: | , , , , , , , , , , |
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Médium: | Artigo |
Jazyk: | angličtina |
Vydáno: |
2018
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On-line přístup: | https://doi.org/10.1186/s13045-018-0563-y https://jhoonline.biomedcentral.com/track/pdf/10.1186/s13045-018-0563-y |
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