A CS1-NKG2D Bispecific Antibody Collectively Activates Cytolytic Immune Cells against Multiple Myeloma

Abstract Multiple myeloma (MM) is an incurable hematologic malignancy of plasma cells, with an estimated 30,000 new cases diagnosed each year in the United States, signifying the need for new therapeutic approaches. We hypothesized that targeting MM using a bispecific antibody (biAb) to simultaneous...

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Autors principals: Wing Keung Chan, Siwen Kang, Youssef Youssef, Erin N. Glankler, Emma R. Barrett, Alex M. Carter, Elshafa H. Ahmed, Aman Prasad, Luxi Chen, Jianying Zhang, Don M. Benson, Michael A. Caligiuri, Jianhua Yu
Format: Artigo
Idioma:anglès
Publicat: 2018
Accés en línia:https://doi.org/10.1158/2326-6066.cir-17-0649
https://cancerimmunolres.aacrjournals.org/content/canimm/6/7/776.full.pdf
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