Clinical Pharmacokinetics and Dose Recommendations for Posaconazole in Infants and Children

The objectives of this study were to investigate the population pharmacokinetics of posaconazole in immunocompromised children, evaluate the influence of patient characteristics on posaconazole exposure and perform simulations to recommend optimal starting doses. Posaconazole plasma concentrations f...

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Main Authors: Sophida Boonsathorn, Iek Cheng, Frank Kloprogge, C. Alonso, Charmion Lee, Bilyana Doncheva, John Booth, Robert Chiesa, Adam Irwin, Joseph F. Standing
Format: Artigo
Jezik:angleščina
Izdano: 2018
Online dostop:https://doi.org/10.1007/s40262-018-0658-1
https://link.springer.com/content/pdf/10.1007/s40262-018-0658-1.pdf
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