Sleeve Gastrectomy Improves Glycemia Independent of Weight Loss by Restoring Hepatic Insulin Sensitivity

Bariatric surgery dramatically improves glycemic control, yet the underlying molecular mechanisms remain controversial because of confounding weight loss. We performed sleeve gastrectomy (SG) on obese and diabetic leptin receptor–deficient mice (db/db). One week postsurgery, mice weighed 5% less and...

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Main Authors: Samir Abu‐Gazala, E. Philip Horwitz, Rachel Ben‐Haroush Schyr, Aya Bardugo, Hadar Israeli, Ayat Hija, Jonathan Schug, Soona Shin, Yuval Dor, Klaus H. Kaestner, Danny Ben‐Zvi
Format: Artigo
Language:English
Published: 2018
Online Access:https://doi.org/10.2337/db17-1028
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