Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation
Neural stem cell (NSC) transplantation can influence immune responses and suppress inflammation in the CNS. Metabolites, such as succinate, modulate the phenotype and function of immune cells, but whether and how NSCs are also activated by such immunometabolites to control immunoreactivity and infla...
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Hauptverfasser: | , , , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Sprache: | Englisch |
Veröffentlicht: |
2018
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Online-Zugang: | https://doi.org/10.1016/j.stem.2018.01.020 |
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