Aspirin Recapitulates Features of Caloric Restriction

The age-associated deterioration in cellular and organismal functions associates with dysregulation of nutrient-sensing pathways and disabled autophagy. The reactivation of autophagic flux may prevent or ameliorate age-related metabolic dysfunctions. Non-toxic compounds endowed with the capacity to...

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Main Authors: Federico Pietrocola, Francesca Castoldi, Maria Markaki, Sylvie Lachkar, Guo Chen, David Enot, Sylvère Durand, Noélie Bossut, Mingming Tong, Shoaib Ahmad Malik, Friedemann Loos, Nicolas Dupont, Guillermo Mariño, Nejma Abdelkader, Frank Madeo, Maria Chiara Maiuri, Romano T. Kroemer, Patrice Codogno, Junichi Sadoshima, Nektarios Tavernarakis, Guido Kroemer
Formato: Artigo
Idioma:inglés
Publicado: 2018
Acceso en liña:https://doi.org/10.1016/j.celrep.2018.02.024
https://www.cell.com/article/S221112471830192X/pdf
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