Chaski, a novel Drosophila lactate/pyruvate transporter required in glia cells for survival under nutritional stress

The intercellular transport of lactate is crucial for the astrocyte-to-neuron lactate shuttle (ANLS), a model of brain energetics according to which neurons are fueled by astrocytic lactate. In this study we show that the Drosophila chaski gene encodes a monocarboxylate transporter protein (MCT/SLC1...

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Main Authors: María Graciela Delgado, Carlos Oliva, Estefanía López, Andrés Ibacache, Alex Galaz, Ricardo Delgado, L. Felipe Barros, Jimena Sierralta
格式: Artigo
語言:英语
出版: 2018
在線閱讀:https://doi.org/10.1038/s41598-018-19595-5
https://www.nature.com/articles/s41598-018-19595-5.pdf
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