Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis

Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis

Spondyloarthritis encompasses a group of common inflammatory diseases thought to be driven by IL-17A-secreting type-17 lymphocytes. Here we show increased numbers of GM-CSF-producing CD4 and CD8 lymphocytes in the blood and joints of patients with spondyloarthritis, and increased numbers of IL-17A+G...

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Hlavní autoři: Hussein Al‐Mossawi, L. Chen, Hai Fang, Anne J. Ridley, Jelle de Wit, Nicole Yager, Ariane Hammitzsch, Irina Pulyakhina, Benjamin P. Fairfax, Davide Simone, Yao Yi, Soham Bandyopadhyay, K Doig, Roger Gundle, Benjamin Kendrick, Fiona Powrie, Julian C. Knight, Paul Bowness
Médium: Artigo
Jazyk:angličtina
Vydáno: 2017
On-line přístup:https://doi.org/10.1038/s41467-017-01771-2
https://www.nature.com/articles/s41467-017-01771-2.pdf
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https://doi.org/10.1038/s41467-017-01771-2
https://www.nature.com/articles/s41467-017-01771-2.pdf

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