Mutations in the netrin-1 gene cause congenital mirror movements

Mutations in the netrin-1 gene cause congenital mirror movements

Netrin-1 is a secreted protein that was first identified 20 years ago as an axon guidance molecule that regulates midline crossing in the CNS. It plays critical roles in various tissues throughout development and is implicated in tumorigenesis and inflammation in adulthood. Despite extensive studies...

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Hlavní autoři: Aurélie Méneret, Elizabeth A. Franz, Oriane Trouillard, Thomas Oliver, Yvrick Zagar, Stephen P. Robertson, Quentin Welniarz, R. J. M. Gardner, Cécile Gallea, Myriam Srour, Christel Depienne, Christine L. Jasoni, Caroline Dubacq, Florence Riant, Jean‐Charles Lamy, Marie‐Pierre Morel, Raphaël Guérois, Jessica Andréani, Coralie Fouquet, Mohamed Doulazmi, Marie Vidailhet, Guy A. Rouleau, Alexis Brice, Alain Chédotal, Isabelle Dusart, Emmanuel Roze, David Markie
Médium: Artigo
Jazyk:angličtina
Vydáno: 2017
On-line přístup:https://doi.org/10.1172/jci95442
http://www.jci.org/articles/view/95442/files/pdf
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https://doi.org/10.1172/jci95442
http://www.jci.org/articles/view/95442/files/pdf

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