Abro1 maintains genome stability and limits replication stress by protecting replication fork stability

Protection of the stalled replication fork is crucial for responding to replication stress and minimizing its impact on chromosome instability, thus preventing diseases, including cancer. We found a new component, Abro1, in the protection of stalled replication fork integrity. Abro1 deficiency resul...

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Hlavní autoři: Shengfeng Xu, Xiao Y. Wu, Ling Wu, A. Pons Castillo, Jianxin Liu, Erin Atkinson, Atanu Paul, Dan Su, Katharina Schlacher, Yoshihiro Komatsu, M. James You, Bin Wang
Médium: Artigo
Jazyk:angličtina
Vydáno: 2017
On-line přístup:https://doi.org/10.1101/gad.299172.117
http://genesdev.cshlp.org/content/31/14/1469.full.pdf
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