BRD3 and BRD4 BET Bromodomain Proteins Differentially Regulate Skeletal Myogenesis
Myogenic differentiation proceeds through a highly coordinated cascade of gene activation that necessitates epigenomic changes in chromatin structure. Using a screen of small molecule epigenetic probes we identified three compounds which inhibited myogenic differentiation in C2C12 myoblasts; (+)-JQ1...
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| Main Authors: | , , , , , , , |
|---|---|
| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2017
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| 在线阅读: | https://doi.org/10.1038/s41598-017-06483-7 |
| 标签: |
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