Proteomics Profiling of Exosomes from Primary Mouse Osteoblasts under Proliferation versus Mineralization Conditions and Characterization of Their Uptake into Prostate Cancer Cells

Proteomics Profiling of Exosomes from Primary Mouse Osteoblasts under Proliferation versus Mineralization Conditions and Characterization of Their Uptake into Prostate Cancer Cells

Osteoblasts communicate both with normal cells in the bone marrow and with tumor cells that metastasized to bone. Here we show that osteoblasts release exosomes, we termed osteosomes, which may be a novel mechanism by which osteoblasts communicate with cells in their environment. We have isolated ex...

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Hlavní autoři: Mehmet Asım Bilen, Tianhong Pan, Yu-Chen Lee, Song-Chang Lin, Guoyu Yu, Jing Pan, David H. Hawke, Bih-Fang Pan, Jody V. Vykoukal, Kavanya Gray, Robert L. Satcher, Gary E. Gallick, Li‐Yuan Yu‐Lee, Sue-Hwa Lin
Médium: Artigo
Jazyk:angličtina
Vydáno: 2017
On-line přístup:https://doi.org/10.1021/acs.jproteome.6b00981
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https://doi.org/10.1021/acs.jproteome.6b00981

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