Interaction between Multimeric von Willebrand Factor and Complement: A Fresh Look to the Pathophysiology of Microvascular Thrombosis

Abstract von Willebrand factor (VWF), a multimeric protein with a central role in hemostasis, has been shown to interact with complement components. However, results are contrasting and inconclusive. By studying 20 patients with congenital thrombotic thrombocytopenic purpura (cTTP) who cannot cleave...

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Main Authors: Serena Bettoni, Miriam Galbusera, Sara Gastoldi, Roberta Donadelli, Chiara Tentori, Giuseppina Spartà, Elena Bresin, Caterina Mele, Marta Alberti, Agustín Tortajada, Hugo Yébenes, Giuseppe Remuzzi, Marina Noris
格式: Artigo
语言:英语
出版: 2017
在线阅读:https://doi.org/10.4049/jimmunol.1601121
https://www.jimmunol.org/content/jimmunol/199/3/1021.full.pdf
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