Interaction between Multimeric von Willebrand Factor and Complement: A Fresh Look to the Pathophysiology of Microvascular Thrombosis
Abstract von Willebrand factor (VWF), a multimeric protein with a central role in hemostasis, has been shown to interact with complement components. However, results are contrasting and inconclusive. By studying 20 patients with congenital thrombotic thrombocytopenic purpura (cTTP) who cannot cleave...
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Main Authors: | , , , , , , , , , , , , |
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格式: | Artigo |
语言: | 英语 |
出版: |
2017
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在线阅读: | https://doi.org/10.4049/jimmunol.1601121 https://www.jimmunol.org/content/jimmunol/199/3/1021.full.pdf |
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