Analysis of mutant allele fractions in driver genes in colorectal cancer – biological and clinical insights

Analysis of mutant allele fractions in driver genes in colorectal cancer – biological and clinical insights

Sequencing of tumors is now routine and guides personalized cancer therapy. Mutant allele fractions (MAFs, or the 'mutation dose') of a driver gene may reveal the genomic structure of tumors and influence response to targeted therapies. We performed a comprehensive analysis of MAFs of driv...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Rodrigo Dienstmann, Elena Élez, Guillem Argilés, Ignacio Matos, Enrique Sanz‐García, Carolina Ortiz, Teresa Macarulla, Jaume Capdevila, María Alsina, Tamara Saurí, Helena Verdaguer, Marta Vilaró, Fiorella Ruíz‐Pace, Cristina Viaplana, Ariadna García, Stefania Landolfi, Héctor G. Pálmer, Paolo Nucíforo, Jordi Rodón, Ana Vivancos, Josep Tabernero
Hōputu: Artigo
Reo:Ingarihi
I whakaputaina: 2017
Urunga tuihono:https://doi.org/10.1002/1878-0261.12099
https://febs.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1878-0261.12099
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Ipurangi

https://doi.org/10.1002/1878-0261.12099
https://febs.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1878-0261.12099

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