Analysis of mutant allele fractions in driver genes in colorectal cancer – biological and clinical insights

Analysis of mutant allele fractions in driver genes in colorectal cancer – biological and clinical insights

Sequencing of tumors is now routine and guides personalized cancer therapy. Mutant allele fractions (MAFs, or the 'mutation dose') of a driver gene may reveal the genomic structure of tumors and influence response to targeted therapies. We performed a comprehensive analysis of MAFs of driv...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Rodrigo Dienstmann, Elena Élez, Guillem Argilés, Ignacio Matos, Enrique Sanz‐García, Carolina Ortiz, Teresa Macarulla, Jaume Capdevila, María Alsina, Tamara Saurí, Helena Verdaguer, Marta Vilaró, Fiorella Ruíz‐Pace, Cristina Viaplana, Ariadna García, Stefania Landolfi, Héctor G. Pálmer, Paolo Nucíforo, Jordi Rodón, Ana Vivancos, Josep Tabernero
Aineistotyyppi: Artigo
Kieli:englanti
Julkaistu: 2017
Linkit:https://doi.org/10.1002/1878-0261.12099
https://febs.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1878-0261.12099
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Internet

https://doi.org/10.1002/1878-0261.12099
https://febs.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1878-0261.12099

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