Analysis of mutant allele fractions in driver genes in colorectal cancer – biological and clinical insights

Analysis of mutant allele fractions in driver genes in colorectal cancer – biological and clinical insights

Sequencing of tumors is now routine and guides personalized cancer therapy. Mutant allele fractions (MAFs, or the 'mutation dose') of a driver gene may reveal the genomic structure of tumors and influence response to targeted therapies. We performed a comprehensive analysis of MAFs of driv...

Full description

Saved in:
Bibliographic Details
Main Authors: Rodrigo Dienstmann, Elena Élez, Guillem Argilés, Ignacio Matos, Enrique Sanz‐García, Carolina Ortiz, Teresa Macarulla, Jaume Capdevila, María Alsina, Tamara Saurí, Helena Verdaguer, Marta Vilaró, Fiorella Ruíz‐Pace, Cristina Viaplana, Ariadna García, Stefania Landolfi, Héctor G. Pálmer, Paolo Nucíforo, Jordi Rodón, Ana Vivancos, Josep Tabernero
Format: Artigo
Language:English
Published: 2017
Online Access:https://doi.org/10.1002/1878-0261.12099
https://febs.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1878-0261.12099
Tags: Add Tag
No Tags, Be the first to tag this record!
Be the first to leave a comment!
You must be logged in first

Similar Items