Analysis of mutant allele fractions in driver genes in colorectal cancer – biological and clinical insights
Sequencing of tumors is now routine and guides personalized cancer therapy. Mutant allele fractions (MAFs, or the 'mutation dose') of a driver gene may reveal the genomic structure of tumors and influence response to targeted therapies. We performed a comprehensive analysis of MAFs of driv...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Englisch |
| Veröffentlicht: |
2017
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| Online-Zugang: | https://doi.org/10.1002/1878-0261.12099 https://febs.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1878-0261.12099 |
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