Regulatory Mechanisms and Novel Therapeutic Targeting Strategies for Protein Tyrosine Phosphatases

An appropriate level of protein phosphorylation on tyrosine is essential for cells to react to extracellular stimuli and maintain cellular homeostasis. Faulty operation of signal pathways mediated by protein tyrosine phosphorylation causes numerous human diseases, which presents enormous opportuniti...

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Main Authors: Zhi-Hong Yu, Zhong‐Yin Zhang
格式: Revisão
语言:英语
出版: 2017
在线阅读:https://doi.org/10.1021/acs.chemrev.7b00105
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