Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation
Mucoadhesive particles (MAP) have been widely explored for pulmonary drug delivery because of their perceived benefits in improving particle residence in the lungs. However, retention of particles adhesively trapped in airway mucus may be limited by physiologic mucus clearance mechanisms. In contras...
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2017
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| Online Access: | https://doi.org/10.1126/sciadv.1601556 https://advances.sciencemag.org/content/advances/3/4/e1601556.full.pdf |
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