In vivo binding of PRDM9 reveals interactions with noncanonical genomic sites
In mouse and human meiosis, DNA double-strand breaks (DSBs) initiate homologous recombination and occur at specific sites called hotspots. The localization of these sites is determined by the sequence-specific DNA binding domain of the PRDM9 histone methyl transferase. Here, we performed an extensiv...
Sábháilte in:
| Príomhchruthaitheoirí: | , , , , , , |
|---|---|
| Formáid: | Artigo |
| Teanga: | Béarla |
| Foilsithe / Cruthaithe: |
2017
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| Rochtain ar líne: | https://doi.org/10.1101/gr.217240.116 http://genome.cshlp.org/content/27/4/580.full.pdf |
| Clibeanna: |
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