In vivo binding of PRDM9 reveals interactions with noncanonical genomic sites

In vivo binding of PRDM9 reveals interactions with noncanonical genomic sites

In mouse and human meiosis, DNA double-strand breaks (DSBs) initiate homologous recombination and occur at specific sites called hotspots. The localization of these sites is determined by the sequence-specific DNA binding domain of the PRDM9 histone methyl transferase. Here, we performed an extensiv...

Disgrifiad llawn

Wedi'i Gadw mewn:

Manylion Llyfryddiaeth
Prif Awduron:	Corinne Grey, Julie A. J. Clément, Jérôme Buard, Benjamin Leblanc, Marta Gut, Laurent Duret, Bernard de Massy
Fformat:	Artigo
Iaith:	Saesneg
Cyhoeddwyd:	2017
Mynediad Ar-lein:	https://doi.org/10.1101/gr.217240.116 http://genome.cshlp.org/content/27/4/580.full.pdf
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg

In vivo binding of PRDM9 reveals interactions with noncanonical genomic sites
gan: Grey, Corinne, et al.
Cyhoeddwyd: (2017)

PRDM9 Is a Major Determinant of Meiotic Recombination Hotspots in Humans and Mice
gan: Frédéric Baudat, et al.
Cyhoeddwyd: (2010)

PRDM9, a driver of the genetic map
gan: Grey, Corinne, et al.
Cyhoeddwyd: (2018)

PRDM9, a driver of the genetic map
gan: Corinne Grey, et al.
Cyhoeddwyd: (2018)

PRDM9 Methyltransferase Activity Is Essential for Meiotic DNA Double-Strand Break Formation at Its Binding Sites
gan: Boubou Diagouraga, et al.
Cyhoeddwyd: (2018)

PRDM9 activity depends on HELLS and promotes local 5-hydroxymethylcytosine enrichment
gan: Imai, Yukiko, et al.
Cyhoeddwyd: (2020)

PRDM9 is a Major Determinant of Meiotic Recombination Hotspots in humans and mice
gan: Baudat, F., et al.
Cyhoeddwyd: (2009)

PRDM9 drives the location and rapid evolution of recombination hotspots in salmonid fish
gan: Marie Raynaud, et al.
Cyhoeddwyd: (2025)

Mouse PRDM9 DNA-Binding Specificity Determines Sites of Histone H3 Lysine 4 Trimethylation for Initiation of Meiotic Recombination
gan: Grey, Corinne, et al.
Cyhoeddwyd: (2011)

Mouse PRDM9 DNA-Binding Specificity Determines Sites of Histone H3 Lysine 4 Trimethylation for Initiation of Meiotic Recombination
gan: Corinne Grey, et al.
Cyhoeddwyd: (2011)

Diversity of Prdm9 Zinc Finger Array in Wild Mice Unravels New Facets of the Evolutionary Turnover of this Coding Minisatellite
gan: Buard, Jérôme, et al.
Cyhoeddwyd: (2014)

Diversity of Prdm9 Zinc Finger Array in Wild Mice Unravels New Facets of the Evolutionary Turnover of this Coding Minisatellite
gan: Jérôme Buard, et al.
Cyhoeddwyd: (2014)

Distinct histone modifications define initiation and repair of meiotic recombination in the mouse
gan: Buard, Jérôme, et al.
Cyhoeddwyd: (2009)

Distinct histone modifications define initiation and repair of meiotic recombination in the mouse
gan: Jérôme Buard, et al.
Cyhoeddwyd: (2009)

High prevalence of PRDM9-independent recombination hotspots in placental mammals
gan: Julien Joseph, et al.
Cyhoeddwyd: (2024)

The PRDM9 KRAB domain is required for meiosis and involved in protein interactions
gan: Imai, Yukiko, et al.
Cyhoeddwyd: (2017)

The PRDM9 KRAB domain is required for meiosis and involved in protein interactions
gan: Yukiko Imai, et al.
Cyhoeddwyd: (2017)

Molecular Basis for the Regulation of the H3K4 Methyltransferase Activity of PRDM9
gan: Hong Wu, et al.
Cyhoeddwyd: (2013)

The complex binding of PRDM9
gan: Ségurel, Laure
Cyhoeddwyd: (2013)

Variability of PRDM9 in buffaloes
gan: Leonardo Santana, et al.
Cyhoeddwyd: (2025)

Interallelic and Intergenic Incompatibilities of the Prdm9 (Hst1) Gene in Mouse Hybrid Sterility
gan: Flachs, Petr, et al.
Cyhoeddwyd: (2012)

Interallelic and Intergenic Incompatibilities of the Prdm9 (Hst1) Gene in Mouse Hybrid Sterility
gan: Petr Flachs, et al.
Cyhoeddwyd: (2012)

Repeated losses of PRDM9-directed recombination despite the conservation of PRDM9 across vertebrates
gan: Baker, Zachary, et al.
Cyhoeddwyd: (2017)

Repeated losses of PRDM9-directed recombination despite the conservation of PRDM9 across vertebrates
gan: Zachary Baker, et al.
Cyhoeddwyd: (2017)

Pinpointing the PRDM9-PRDM7 Gene Duplication Event During Primate Divergence
gan: Heerschop, Sacha, et al.
Cyhoeddwyd: (2021)

Cataloging Human PRDM9 Allelic Variation Using Long-Read Sequencing Reveals PRDM9 Population Specificity and Two Distinct Groupings of Related Alleles
gan: Alleva, Benjamin, et al.
Cyhoeddwyd: (2021)

Discovery of a chemical probe for PRDM9
gan: Abdellah Allali‐Hassani, et al.
Cyhoeddwyd: (2019)

Discovery of a chemical probe for PRDM9
gan: Allali-Hassani, Abdellah, et al.
Cyhoeddwyd: (2019)

Rat PRDM9 shapes recombination landscapes, duration of meiosis, gametogenesis, and age of fertility
gan: Mihola, Ondrej, et al.
Cyhoeddwyd: (2021)

High Diversity at PRDM9 in Chimpanzees and Bonobos
gan: Groeneveld, Linn Fenna, et al.
Cyhoeddwyd: (2012)

Characterization of Prdm9 in Equids and Sterility in Mules
gan: Steiner, Cynthia C., et al.
Cyhoeddwyd: (2013)

Primate evolution of the recombination regulator PRDM9
gan: Schwartz, Jerrod J., et al.
Cyhoeddwyd: (2014)

Interrogating the Functions of PRDM9 Domains in Meiosis
gan: Thibault-Sennett, Sarah, et al.
Cyhoeddwyd: (2018)

PRDM9 and its role in genetic recombination
gan: Paigen, Kenneth, et al.
Cyhoeddwyd: (2018)

PRDM9 and Its Role in Genetic Recombination
gan: Kenneth Paigen, et al.
Cyhoeddwyd: (2018)

Primate evolution of the recombination regulator PRDM9
gan: Jerrod J. Schwartz, et al.
Cyhoeddwyd: (2014)

Automation in genotyping of single nucleotide polymorphisms
gan: Marta Gut
Cyhoeddwyd: (2001)

DNA analysis by MALDI-TOF mass spectrometry
gan: Marta Gut
Cyhoeddwyd: (2004)

Methylation of PRDM2, PRDM5 and PRDM16 genes in lung cancer cells
gan: Tan, Shuang-Xiang, et al.
Cyhoeddwyd: (2014)

Chromosome Organization in Early Meiotic Prophase
gan: Grey, Corinne, et al.
Cyhoeddwyd: (2021)