The Diabetes-Linked Transcription Factor PAX4: From Gene to Functional Consequences
Paired box 4 (PAX4) is a key factor in the generation of insulin producing β-cells during embryonic development. In adult islets, PAX4 expression is sequestered to a subset of β-cells that are prone to proliferation and more resistant to stress-induced apoptosis. The importance of this transcription...
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| Main Authors: | , , , , |
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| 格式: | Revisão |
| 语言: | 英语 |
| 出版: |
2017
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| 在线阅读: | https://doi.org/10.3390/genes8030101 https://www.mdpi.com/2073-4425/8/3/101/pdf?version=1489054059 |
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