Differences in the rare variant spectrum among human populations

Mutations occur at vastly different rates across the genome, and populations, leading to differences in the spectrum of segregating polymorphisms. Here, we investigate variation in the rare variant spectrum in a sample of human genomes representing all major world populations. We find at least two d...

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Main Authors: Iain Mathieson, David Reich
格式: Artigo
语言:英语
出版: 2017
在线阅读:https://doi.org/10.1371/journal.pgen.1006581
https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1006581&type=printable
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