Nuclear Factor Erythroid 2-related Factor 2 Deficiency Exacerbates Lupus Nephritis in B6/lpr mice by Regulating Th17 Cell Function

Abstract Lupus nephritis (LN) is the major clinical manifestation of systemic lupus erythematosus. LN is promoted by T helper 17 (Th17) cells, which are the major pro-inflammatory T cell subset contributing to autoimmunity regulation. Nuclear factor erythroid 2-related factor 2 (NRF2) is critical fo...

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Main Authors: Mei Zhao, Huanpeng Chen, Qingfeng Ding, Xiaoxie Xu, Bolan Yu, Zhaofeng Huang
格式: Artigo
語言:英语
出版: 2016
在線閱讀:https://doi.org/10.1038/srep38619
https://www.nature.com/articles/srep38619.pdf
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