The cellular protein nucleolin preferentially binds long-looped G-quadruplex nucleic acids

G-quadruplexes (G4s) are four-stranded nucleic acid structures that form in G-rich sequences. Nucleolin (NCL) is a cellular protein reported for its functions upon G4 recognition, such as induction of neurodegenerative diseases, tumor and virus mechanisms activation. We here aimed at defining NCL/G4...

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Main Authors: Sara Lago, Elena Tosoni, Matteo Nadai, Manlio Palumbo, Sara N. Richter
格式: Artigo
语言:英语
出版: 2016
在线阅读:https://doi.org/10.1016/j.bbagen.2016.11.036
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