Evolution of Mutation Rates in Rapidly Adapting Asexual Populations

Abstract Mutator and antimutator alleles often arise and spread in both natural microbial populations and laboratory evolution experiments. The evolutionary dynamics of these mutation rate modifiers are determined by indirect selection on linked beneficial and deleterious mutations. These indirect s...

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Main Authors: Benjamin H. Good, Michael M. Desai
格式: Artigo
語言:英语
出版: 2016
在線閱讀:https://doi.org/10.1534/genetics.116.193565
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