Evolution of Mutation Rates in Rapidly Adapting Asexual Populations
Abstract Mutator and antimutator alleles often arise and spread in both natural microbial populations and laboratory evolution experiments. The evolutionary dynamics of these mutation rate modifiers are determined by indirect selection on linked beneficial and deleterious mutations. These indirect s...
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Main Authors: | , |
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格式: | Artigo |
語言: | 英语 |
出版: |
2016
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在線閱讀: | https://doi.org/10.1534/genetics.116.193565 |
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