Evolution of Mutation Rates in Rapidly Adapting Asexual Populations

Abstract Mutator and antimutator alleles often arise and spread in both natural microbial populations and laboratory evolution experiments. The evolutionary dynamics of these mutation rate modifiers are determined by indirect selection on linked beneficial and deleterious mutations. These indirect s...

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Bibliographic Details
Main Authors: Benjamin H. Good, Michael M. Desai
Format: Artigo
Language:English
Published: 2016
Online Access:https://doi.org/10.1534/genetics.116.193565
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