Biosimilars for psoriasis: clinical studies to determine similarity
Biosimilars are drugs that are similar, but not identical, to originator biologics. Pre-clinical analytical studies are required to show similarity on a molecular and structural level, but efficacy and safety studies in humans are essential to ultimately determine biosimilarity. In this review writt...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , , , , |
|---|---|
| स्वरूप: | Revisão |
| भाषा: | अंग्रेज़ी |
| प्रकाशित: |
2016
|
| ऑनलाइन पहुंच: | https://doi.org/10.1111/bjd.15067 |
| टैग: |
टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!
|
| _version_ | 1837946985858990080 |
|---|---|
| access_facet | Acesso Aberto |
| author | Andrew Blauvelt L. Puig Sergio Chimenti Ronald Vender Murlidhar Rajagopalan Ricardo Romiti Lone Skov Claus Zachariae Helen Young Errol P. Prens Arnon D. Cohen J. van der Walt Jashin J. Wu |
| author_facet | Andrew Blauvelt L. Puig Sergio Chimenti Ronald Vender Murlidhar Rajagopalan Ricardo Romiti Lone Skov Claus Zachariae Helen Young Errol P. Prens Arnon D. Cohen J. van der Walt Jashin J. Wu |
| cited_by_count_is | 19 |
| collection | OpenAlex |
| description | Biosimilars are drugs that are similar, but not identical, to originator biologics. Pre-clinical analytical studies are required to show similarity on a molecular and structural level, but efficacy and safety studies in humans are essential to ultimately determine biosimilarity. In this review written by members of the International Psoriasis Council, we discuss how biosimilars are evaluated in a clinical setting, with emphasis on extrapolation of indication, interchangeability, and optimal clinical trial design. This article is protected by copyright. All rights reserved. |
| format | Revisão |
| frbr_group_id_str | doi-10.1111/bjd.15067 |
| id | openalex-W2519779602 |
| institution | Oregon Medical Research Center |
| issn_str | 0007-0963 |
| issue_str | 1 |
| journal_title_str | British Journal of Dermatology |
| language | eng |
| publishDate | 2016 |
| publisher_str | Oxford University Press |
| spellingShingle | Biosimilars for psoriasis: clinical studies to determine similarity Andrew Blauvelt L. Puig Sergio Chimenti Ronald Vender Murlidhar Rajagopalan Ricardo Romiti Lone Skov Claus Zachariae Helen Young Errol P. Prens Arnon D. Cohen J. van der Walt Jashin J. Wu |
| title | Biosimilars for psoriasis: clinical studies to determine similarity |
| title_full | Biosimilars for psoriasis: clinical studies to determine similarity |
| title_fullStr | Biosimilars for psoriasis: clinical studies to determine similarity |
| title_full_unstemmed | Biosimilars for psoriasis: clinical studies to determine similarity |
| title_short | Biosimilars for psoriasis: clinical studies to determine similarity |
| topic_facet | Biosimilar Psoriasis Similarity (geometry) Medicine Dermatology MEDLINE Intensive care medicine Computer science Internal medicine Artificial intelligence Chemistry Image (mathematics) Biochemistry |
| url | https://doi.org/10.1111/bjd.15067 |
| volume_str | 177 |